Isaac Hayes, rock & roll icon and voice of the Chef on South Park, is suddenly offended by the cartoon and wants out.

I don't watch the show, but I wouldn't think it would be a place for sensitive folks. This (rather angry sounding) quote from co-creator Matt Stone might have it right:

"This is 100 percent having to do with his faith of Scientology," Stone told the Associated Press. "He has no problem--and he's cashed plenty of checks--with our show making fun of Christians."